CVE-2026-31966General(htslib / htslib)

LOWCVSS 9.1 · CRITICAL

Signal is active with 1 mentions in latest observed window

Immediate actions

  • Track advisory updates for patch or workaround availability

Recommended action window: Monitor and triage in normal cycle

NVD description

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. As one method of removing redundant data, CRAM uses reference-based compression so that instead of storing the full sequence for each alignment record it stores a location in an external reference sequence along with a list of differences to the reference at that location as a sequence of "features". When decoding CRAM records, the reference data is stored in a char array, and parts matching the alignment record sequence are copied over as necessary. Due to insufficient validation of the feature data series, it was possible to make the `cram_decode_seq()` function copy data from either before the start, or after the end of the stored reference either into the buffer used to store the output sequence for the cram record, or into the buffer used to build the SAM `MD` tag. This allowed arbitrary data to be leaked to the calling function. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

0.0/ 10 priority

Sources & remediation

Weakness type (CWE)
CWE-125CWE-129

Priority

LOW

Exploitation

NONE

PoC

NONE

Patch

AVAILABLE

Momentum

NONE

Are you affected?

If you run products in this scope, you should treat this CVE as relevant to your environment.

  • htslib

Threat summary

  • 1 mentions across 1 observed day

What's happening

  • General: 1 classified signal
  • 1 total mentions across 1 day

Affected systems

Vendors
Products
htslib

1 version affected across 1 product

Deep dive

Activity timeline1 mentions / 1d
00111Mentions · 2026-03-18: 103-18
Signal classification1 categories
General
1100.0%
Referenced assets1 URL
By indicator
Full discourse1 post
  • CVE@CVEnew
    General

    CVE-2026-31966 HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. As one method of removi… https://www.cve.org/CVERecord?id=CVE-2026-31966

    Post summary

    The text only cites CVE‑2026‑31966 and offers a brief context about HTSlib and CRAM, but provides no actionable or detailed information about the vulnerability.

    0000068
    56.7K followersView on X
CPE platform detail2 entries

2 of 2 entries

PartVendorProductVersionTarget SWTarget HW
Apphtslibhtslib---
Apphtslibhtslib1.23--

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